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Iron at the crossroads of ferroptosis: Driver of lipid peroxidation or defender of redox homeostasis

KPV has been investigated as a research tool in models of intestinal inflammation, including in targeted nanoparticle-based delivery systems (Xiao et al

Also, mTORC1 activates the ribosomal protein S6 kinase beta-1 (S6K1) and the eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1), promoting the translation of MCL-1 mRNA on ribosomes and the synthesis of Mcl-1 [301]

S.BeecherC.et al (2005)

Protein lipoylation, a highly conserved lysine post-translational modification, attaches lipoic acid moieties to lysine residues of substrate proteins, modulating their functions