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All these might be its modulatory effects
An additional experiment conducted during this study showed that by treating 3T3-L1 adipocytes with NAC (600 M), a methylglyoxal impairment in insulin signalling was relieved, as shown by decreased insulin-induced insulin receptor substrate-1 tyrosine phosphorylation and decreased activity of phosphatidylinositol 3-kinase (66)

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Payahoo, L., Khajebishak, Y

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