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It is characterized by a deficiency in serum testosterone levels and symptoms such as low sexual desire, erectile dysfunction, muscle mass loss, obesity, osteoporosis, and depression [13]

Nakamura, H

Introduction Liver disease is a major cause of death worldwide [1], and cell death plays a key role in driving the progression of various forms of liver disease

Sumoylation Post-translational protein modification by attachment of SUMO (small ubiquitin-related modifier) proteins, involving the formation of isopeptide bonds with -amino groups of acceptor Lys residues of target proteins

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