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However, despite widespread use of ivermectin over the past few decades for several indications, reports of resistance to date have been limited and contentious (Crump et al

These experiments have shown that both valgus stress and axial loading can lead to partial or complete ACL tears, validating the findings from finite element models

, a bioactive compound that has an inhibitory effect on melanin (the pigment that gives color to the skin) synthesis (5)

doi: 10.1074/jbc.RA117.000826

Ann Thorac Surg 108(2):370-376, 2019
