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Ocular / Retinal Models Epithalon has also been tested in visual system research: In rodent models of retinal degeneration, Epithalon has been associated with preservation of retinal structure and improvement in electrophysiologic measures of retinal function in a subset of treated subjects

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Agonist-induced restoration of hippocampal neurogenesis and cognitive improvement in a model of cholinergic denervation

Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery

ArfGAP1 is known to function as a GAP for the Golgi-localized small GTPase Arf1, that mediates the dissociation of the COPI coatomer complex from Golgi-derived vesicles, a prerequisite for vesicle fusion with target compartments such as the endoplasmic reticulum (ER) [3640]