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Antitumor agents targeting GST in context are listed in Table 2

Three types are of special interest: the van der Waals model, the solvent accessible model and the molecular surface model

Glyphosate interferes with the bodys ability to use Glycine, and therefore its ability to synthesize and utilize GSH

With the help of enzymes, L-cysteine forms peptide bonds with the amino acids L-glycine and L-glutamic acid to make glutathione

It consists of glyoxalase 1 (Glo-1), glyoxalase 2 (Glo-2), and reduced glutathione (GSH) (Figure 2), which perform an essential metabolic function in cells by detoxifying methylglyoxal (MG) and other endogenous harmful metabolites into non-toxic d-lactate [227,228]