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Robust in vivo efficacy data, standardized pharmacokinetic and toxicology characterization, stability studies, and rigorous clinical trials are urgently needed

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In a subsequent group given three 50 g IN doses (1 day before lesioning, 1 h before lesioning, 1 day post-lesioning), lesioned rats had even greater neuroprotective and regenerative effects, showing that multiple smaller doses in short intervals were more effective than a larger single dose [36]

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The increase in (relative risk) between the highest and lowest fibrinogen levels was 301% for men and 342% for women (CVD death) and 259% for men and 220% for women (death from any cause) [43]

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Mechanisms of salinity tolerance

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