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Furthermore, a meta-analysis including 38 studies with schizophrenia cases and controls showed the association between C677T polymorphism and risk of schizophrenia in all three ethnic populationsAfrican, Asian, and Caucasian 54

It does not have the same level of clinical evidence as approved medications for inflammatory bowel disease, autoimmune disease, or other diagnosed inflammatory conditions

Nonetheless, this study suggests that the level of inflammation may influence the required treatment dose

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