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B12 deficiency can also cause water retention, constipation, muscle weakness, fatigue, and weight loss

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The relevance of pharmacognosy in pharmacological research on herbal medicinal products

Research in 2022 concluded that high B12 in cancer patients is often an epiphenomenon. In other words, the vitamin appears alongside the disease but does not necessarily trigger it

, in efflux from cancer cells as the cause for their chemo-resistance) and in the mechanisms responsible for the dose-limiting kidney toxicity of cisplatin and for its years-long terminal half life [63,64,65]