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Too high a peptide concentration, in a dose higher than recommended, as with any other substance, is simply unnecessary for the body

Rather than directly supplying NAD+ precursors (like NMN or NR), it works by blocking an enzyme that consumes nicotinamide, theoretically preserving the substrate pool for endogenous NAD+ production

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For people with MTHFR mutations, supplementation with methylfolate will be more beneficial than folic acid, as they might have a reduced capacity to turn folic acid into methylfolate