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The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature

There are several examples of cereblon-based PROTACs recently reported in the literature starting from the building block 4-fluorothalidomide (Table 2)

GannonJMForrestPERoy ChengappaKN

Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, et al

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Figure 1 from Changes of melanocytic lesions inducedby Melanotan injections and sun bed use ina teenage patient with FAMMM syndrome

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A peptide that makes you tan. Sounds great. What could go wrong? When it’s activating your melanocytes to increase pigment in your skin, it may also be causing cancer— melanoma. I’ve had patients have

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