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As its accumulation progressively increases with age, lipofuscin is considered a reliable marker of aging (Porta, 2002)
Around 1% of people will develop severe neurological symptoms, including encephalitis and myocarditis
On the other hand, as cellular reserve energy sources LDs transport FAs released from degradation to mitochondria for -oxidation and ATP production through their interaction during nutrient stress [109]

Active infections in or near treatment areas require resolution before proceeding

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