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Oxidative stress is another factor for the AD pathology

Additionally, activating the SIRT1/Nrf2/p62 pathway can promote the healing of diabetic foot ulcers, possibly mediated by autophagy-dependent ferroptosis ( Together, the diverse roles of SIRT1 across multiple disease types underscore its significance as a promising therapeutic target
Curr Dev Nutr

For central nervous system infections caused by the CARD9 defect, a combination of surgical drainage and long-term antifungal treatment is required (Shen et al., 2020)

It is considered safe for human use because it exhibits low toxicity and does not have teratogenic, carcinogenic, or mutagenic effects [24]Limonene possesses pharmacological properties, including antibacterial, anticancer, antioxidant, anti-inflammatory, and neuroprotective [25,26,27,28]