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However, the simultaneous coordination of Cu 2+ with four imidazolyls generates severe steric hindrance 25

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With respect to the studied compounds, compound A (Ferrostatin) has been reported to show anti-ferroptotic activity inhibit neurotoxicity induced by glutamate in HT-22 mouse hippocampal cell culture [20]

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doi: 10.1038/s41420-025-02550-5

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