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Patients experiencing unexplained weight changes should consult their GP, who may arrange thyroid function testing to rule out thyroid disorders before attributing symptoms solely to metabolic issues

This consideration becomes less relevant as patients gain confidence and experience with self-administration

Kraemer WJ, Spiering BA, Volek JS, Ratamess NA, Sharman MJ, Rubin MR, French DN, Silvestre R, Hatfield DL, Van Heest JL, Vingren JL, Judelson DA, Deschenes MR, Maresh CM

The use of siRNA to induce gene knockdown by targeting mRNA for degradation has received the most interest in this category, and the chemically synthesized siRNA Inclisiran has already been approved for use in hypercholesterolemia

Callea, C