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One approach to achieve this is to ensure that the cells have adequate levels of antioxidants, particularly GSH, that can capture ROS and break them down or convert them to less harmful molecules

Combined with Vitamin C, it enhances overall antioxidant defense

Following from previous work that sought to identify sequence determinants of S fibrillation, a library-based -lactamase tripartite fusion construct in which S was inserted between Blac fragments and probed for aggregation, identified mutations within the P1/P2 regions that impacted on the ability of S to aggregate

10.1016/j.yjmcc.2012.09.002 J

Fertil Steril, May;89(5):1287-98