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Neuropharmacology 76 Pt C:610627

(Source 2) Spinach is a nutrient-dense leafy green vegetable, in the same family as beets and chard and originated as a wild plant in Asia

Copper is an essential trace mineral involved in more than a dozen enzymatic reactions in the human body including those governing connective tissue formation, antioxidant defense, cellular respiration, and blood clotting

Consequently, VRK2 expression emerges as a dual-function biomarker: its targeted inhibition shows therapeutic efficacy in VRK2-high malignancies, while its deficiency serves as a predictive indicator for metabolic-targeted interventions

Together, these findings highlight the diverse nature of ASD pathophysiology, in which inflammatory, metabolic, and synaptic mechanisms all contribute to the behavioral symptom presentation (Fig