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For example, with linoleoyl-CoA (illustrated), three cycles of oxidation yield a 3 Z ,6 Z 12:2 intermediate, which must be isomerized by an enoyl-CoA isomerase to 2 E ,6 Z -12:2-CoA

Anticonvulsant and antiepileptic actions of 2-deoxy-D-glucose in epilepsy models

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In hypogonadal men with diabetes or in male rodents with androgen deficiency, decreased mitochondrial density, abnormal mitochondrial morphology, and lower ATP production were observed, while exogenous testosterone supplementation effectively alleviated mitochondrial dysfunction and improved glucose and lipid metabolism ( 2 The sex-dimorphic regulatory impact of androgens and AR on glucose and lipid metabolism 2.1 Inhibited androgens/AR negatively affects glucose and lipid metabolism in males The most well-known androgens include testosterone, androstenedione, dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S), and dihydrotestosterone (DHT)