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Embodiment 169 A method of reducing tumor initiating cells in a cell population, the method comprising contacting a cell population, wherein the population comprises tumor initiating cells that express ALPPL2 and cells other than tumor initiating cells, with an anti-ALPPL2 immunoconjugate according to any one of embodiments 136- 164, wherein the effector comprising said immunoconjugate has cytostatic and/or cytotoxic activity and/or immunomodulatory activity, whereby the frequency of tumor initiating cells in the tumor cell population is reduced

1 2 3 "2016 American College of Rheumatology/European League Against Rheumatism Classification Criteria for Primary Sjgren's Syndrome: A Consensus and Data-Driven Methodology Involving Three International Patient Cohorts"

PMID: 189333

BPC-157 (Body Protective Compound - 157) to syntetyczna mieszanka peptydw

The researchers examined records from 1,796 acute heart attack patients seen in a large healthcare system over six years, including 126 who received low-dose colchicine prescriptions, but found no relationship between colchicine and combined cardiovascular events risk