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Development of quantum computational model for analysis of drug delivery: loading of human beta-defensin 3 and mitoxantrone onto composite polymers

Its working mechanism is allosteric facilitation of HGF/c-Met signaling: Dihexa binds HGF with high affinity (reported K d ~65 pM in the original work) and is proposed to potentiate HGF dimerization and c-Met phosphorylation at subthreshold endogenous HGF concentrations

Int Psychogeriatr

Hu Z, Chen Y, Zhu S, Feng X, Zhang B, Huang J

Further outrage could descend on Wells Fargo because the banks chief executive officer and chairman, John Stumpf, would qualify for a handsome pay package were he to step down from his posts at the bank, according to publicly filings with the Securties and Exchange Commission
