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It is interesting to note that synthetic GHRPs had been discovered before the natural ones, which was part of the socalled reversed pharmacology approach, where synthetic GHSs had helped discover the GH secretagogue receptor and the natural GHS ghrelin was identified and isolated thereafter [2, 3, 4, 5, 6]

The p413TEF roGFP2-Grx1 plasmid was generated by subcloning from a p415TEF roGFP2-Grx1 plasmid

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[DOI] [PubMed] [Google Scholar] [88].Nwose EU, Jelinek HF, Richards RS, Tinley P, Kerr PG