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Mitochondrial dysfunction in Alzheimers disease and the rationale for bioenergetics based therapies

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A compound with a 30-minute half-life will reach undetectable plasma concentrations faster than one with a 3-hour half-life

Arsenic trioxide induces apoptosis through a reactive oxygen species-dependent pathway and loss of mitochondrial membrane potential in HeLa cells

It commonly occurs as a complication of long-term use of skin whitening creams containing hydroquinone
