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Several risk factors increase the likelihood of developing neuropathy

Copper peptides are destabilised by low-pH environments, so don't layer them with strong acids or L-ascorbic acid vitamin C serums

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8 This was the first trial in patients with a first acute demyelinating event (now, clinically isolated syndrome) to show efficacy in delaying time-to-clinically definite MS and was recognized as a significant medical advance as it introduced the concept of early treatment and led to revisions in diagnostic criteria for MS

However a safe dosage of vitamin B12 is 1000mcg per day of the methylcobalamin form