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Cant C, Menzies KJ, Auwerx J (2015) NAD + metabolism and the control of energy homeostasis: a balancing act between mitochondria and the nucleus

Malabsorption can cause severe B12 deficiency

By flagging it in Category 2, FDA signaled to pharmacies that BPC-157 is not permitted to be compounded under federal law (Section 503A) due to these safety uncertainties

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Measurements of serum vitamin B 12 may not reliably detect deficiency, and measurement of serum homocysteine and/or methylmalonic acid should be used to confirm deficiency in asymptomatic high-risk patients with low normal levels of vitamin B 12