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While fibroblasts are normally quiescent when responding to injury or inflammation, they upregulate their cytoskeletal components and differentiate into highly contractile myofibroblasts [113] and increase their deposition of collagen and ECM into the tissues

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The main problem in many published papers is the overestimation of GSSG levels, since frequently an adequate treatment is not given to the samples during its collection and processing to avoid the oxidation of the GSH present

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