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Patients may prefer troches for convenience, ease of self-administration, and steady systemic effects that support overall tissue regeneration

Am J Physiol Gastrointest Liver Physiol 2014, 307: G397G409

More recently, a mitochondrial targeted antioxidant Mito-Tempo was reported to protect against AILI even at 3 h post-treatment of APAP compared with NAC alone, suggesting it as a potential therapeutic option for patients at late phase in APAP poisoning [29]

These steps are crucial in drug development but represent a weak link in the production chain, due to long-lasting and expensive phases

[DOI] [PubMed] [Google Scholar] 147.Gordon I., Wyk B.C.V., Bennett R.H., Cordeaux C., Lucas M.V., Eilbott J.A., Zagoory-Sharon O., Leckman J.F., Feldman R., Pelphrey K.A