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am 10.04.2026 Nicole

Additionally, alanine is reported to be significantly increased with metformin monotherapy and combined with sulfonylurea, and branched-chain amino acids (valine, leucine, and isoleucine) are increased with metformin therapy (t Hart et al., 2018b)

Moreover, glutamate can be deaminated in a number of reactions, thus providing a source of nitrogen for nonessential amino acids, purines and pyrimidines [11]

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2015;6:6760.[DOI] 27
