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Fukuda et al., 1994)
Overall, the DDR sensor kinases appear to act to prevent ROS accumulation and protect the genomic integrity, although there are likely to be context specific variations depending on cell type and nature of insult
Dry or sensitive skin needing hydration
In addition to exogenous compounds, many endogenously formed compounds also follow similar metabolic pathways
For instance, Wei and co-workers revealed that the natural compound Eupaformosanin could induce the ubiquitination of mutant p53, and then activate ferroptosis signaling pathway, suggesting a potential therapeutic agent for TNBC [104]
