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Research suggests that training in endurance athletes and, to a lesser extent, in sprinters is associated with a decrease in carnitine levels in the body, meaning supplementation is beneficial

This University of Kansas study is a formal clinical trial examining the combination of d-ribose and ubiquinol in heart failure patients. BLS original patent for its d-ribose ingredient was for its apparent benefits to the mitochondrial function of heart tissue, before the company began marketing its ingredient for exercise, sports performance, and other areas based on further research.

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