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doi: 10.1186/s12931-019-1063-5

Compared to other GH secretagogues, ipamorelin is notable for selectivity it stimulates GH release without significant effects on cortisol, prolactin, or ACTH
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Patients with relative contraindications such as hypertension and severe arrhythmia need to undergo medical assessment before engaging in exercise
To validate these first results and address safety concerns, further comprehensive research is necessary to fully comprehend the range of effects of IGF-1 LR3 on longevity