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NAC may have these potential benefits, but its impact on LDL and oxidized LDL levels may vary among individuals

H 2 O 2 -dependent signaling occurs with a lower intracellular concentration of approximately 1-100 nM, mediating reversible oxidation of the thiolate group to a sulfenic group (Cys-SOH) and covalent linkage of cysteine residues by disulfide bonds (Cys-S-S-Cys) altering its activity and localization (7)

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Glutathione is a key player in hepatic Phase II detoxification

doi: 10.1177/089875640402100402 19