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A recent cross-sectional study involving 124 participants indicated that 56% of patients still exhibited elevated residual gastric contents despite halting incretin agonists for a minimum of 7 days, thus challenging the practice of discontinuing long-acting GLP-1 RAs solely for this duration prior to surgery [19]

This underscores the urgent need for effective treatments for OA

In the AIM-TD study ( N = 298) that included three fixed active treatment arms of 12, 24, and 36 mg, significance in TD rating improvement was achieved for the 24- and 36-mg arms

One of the important oxidant responsive cis elements (transcription factor binding sites) regulating GCL genes is the AP-1 binding site also called the TRE element

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