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For the contradictory findings from Peng et al., we speculate that the energy provided by CAFs is sufficient to support distant metastasis of the tumors or there exists competition between primary tumor cells and CAFs for FA utilization

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This method protects the surrounding tissue and significantly reduces the risk of lumps or uneven degradation

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[15] Although all in all studies conclude that chemotherapy does not change the natural course of the disease there are a few cases in literature where multidisciplinary approach to different type primary cardiac sarcomas including chemotherapy has led to good survival rates [16,17,18]