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The peptide's gastric origins connect to broader systemic effects through this communication pathway

These alterations, in turn, can engage host BA receptors like Farnesoid X Receptor (FXR) and Takeda G protein-coupled Receptor 5 (TGR5/GPBAR1) on immune and cancer cells, thereby influencing anti-tumor immune responses and the efficacy of treatments such as immune checkpoint inhibitors (ICIs)

doi: 10.1016/s0733-8627(05)70205-4

[DOI] [PubMed] [Google Scholar] 119.Elhadidy M.G., Elmasry A., Elsayed H., El-Nablaway M., Hamed S., Elalfy M.M., Rabei M.R

Momordica charantia, a Nutraceutical Approach for Inflammatory Related Diseases