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This drug is almost always associated with some degree of toxicity to the distal renal tubule and accompanying acidosis, hypokalaemia, and polyuria (Butler, 1966

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Its available as a research peptide or for investigational purposes under physician supervision

In transgenic FVB/N mice overexpressing the human HER-2/neu (erbB-2) oncogene, Epithalon administration results in a significant reduction in HER-2/neu mRNA levels, with a reported 3.7-fold decrease relative to saline controls

Empirical evidence of bias in treatment effect estimates in controlled trials with different interventions and outcomes: metaepidemiological study