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l-carnitine administration significantly improved cognitive and renal functions.. Parnetti, L, et al, Pharmacokinetics of IV and oral acetyl-L-carnitine in a multiple dose regimen in patients with senile dementia of Alzheimer type. in European Journal of Clinical Pharmacology , Volume 42, Issue 1, 1992, pp 89 - 93

Another postmortem study has supported these findings by reporting a decreased expression of some subunits of complex I, III, IV, and V in the areas of the cingulate gyrus, motor cortex, and thalamus of the ASD subjects [122]

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