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Description
Functional sepiapterin reductase is a homodimeric enzyme which first converts 6-pyruvoyltetrahydropterin to 1-hydroxy-2-oxopropyltetrahydropterin, which is then reduced to 1-oxo-2-hydroxypropyltetrahydropterin, and then finally to 5,6,7,8-tetrahydrobiopterin, BH 4
In September 2024, the FDA removed them from Category 2 but hasn't added them to Category 1
2022 Mar 7;14(5):1114
doi: 10.1210/jcem-55-1-27
Researchers must comply with all applicable regulations and ethical guidelines when handling and studying this product
