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However, the clinical translation of Kla-targeted therapies faces notable challenges, including the lack of specific inhibitors, potential off-target effects and the complex tissue-specific functions of lactylation
Low B12 causes weakness, fatigue, and depression, but also other symptoms, including numbness or tingling in the hands, feet, and legs
however, mortality rates increased with higher doses, reaching 100% at 500 mg/kg
It can also be used to treat excessive sweating in the hands
Terpstra M, Henry PG, Gruetter R
