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Our findings indicate that the combination of (-)-Vestitol and Salviolone significantly modulates this pathway, likely through a multifaceted effect on various neurotransmitter systems

This is an area where the mechanism is well-characterized, the animal data is robust, and the safety profile appears favorable, but rigorous human trial data remains limited

however, there is evidence of a negatively charged peptide C9, which specifically interacted with DNA [145]