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525,526 However, in a randomized controlled trial involving 244 patients with PDPN, 7 treated with venlafaxine developed clinically significant electrocardiogram changes during treatment, making it less preferred in patients with cardiovascular conditions

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References Amato G, Conte M, Mazziotti G, Lalli E, Vitolo G, Tucker AT, Bellastella A, Carella C, Izzo A (2003) Serum and follicular fluid cytokines in PCOS during stimulated cycles