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Highly active antiretroviral therapy drug combination induces oxidative stress and mitochondrial dysfunction in immortalized human blood-brain barrier endothelial cells

10.1016/j.ajo.2016.11.020 249

BPC-157 peptide, Body Protection Compound-157, and BPC 157 all refer to the same 15-amino acid synthetic peptide with CAS number 137525-51-0 and molecular weight of 1,419.53 Da

Several experiments have demonstrated that it accelerates the healing process of tissues, including transected rat Achilles tendon [5]

All the above factors could be major players in shifting the oxidant/antioxidant balance towards the pro-oxidant side, which in turn exert a compensatory regulatory response by up-regulating the antioxidant defensive mechanism (Hayes and Pulford, 1995)