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doi:10.1111/1541-4337.12448

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Amyloid precursor protein potentiates the neurotrophic activity of NGF

In the SOD1 G93A mouse model of ALS, pyruvate (1000 mg/kg/week i.p.) slowed disease progression and also improved motor symptoms in a rotarod test and survival by 10.5% when it was administered starting at the onset of disease (Park et al., 2007)
