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Description
Cystine-free/GSH-supplemented = 6

Tyrosine kinase inhibitor (TKI) Imatinib, a TKI known for its antitumor activity, has shown promise in interfering with the entry and survival of M.tb in macrophages

doi: 10.1016/j.ebiom.2021.103439 40 TourkiBJiaMKarampitsakosTVeraIMArsenaultAFatimaZet al

[DOI] [PMC free article] [PubMed] [Google Scholar] 40.Zhou S., Zhu S., Cui S., Hou H., Wu H., Hao B., Cai L., Xu Z., Liu L., Jiang L., et al

CYP3A4 is involved in generation of an active metabolite (M1) of the drug, although the structure of M1 and other secondary metabolites have not been reported in the literature
