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Metabolic adaption of CSCs drives tumor resistance, yet the mechanisms of their ferroptosis defense in tumor immune evasion remain elusive
doi: 10.2174/1381612828666220919085019 [DOI] [PubMed] [Google Scholar] 26
This leads to mitochondrial outer membrane permeabilization (MOMP), the release of cytochrome c and other factors and the activation of caspases (3, 7 and 9) through APAF1, culminating in apoptosis
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Why humans need type 5 phosphodiesterase inhibitors
