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The discovery and characterization of a potent DPP-IV inhibitory peptide from oysters for the treatment of type 2 diabetes based on computational and experimental studies

1 Introduction Periodontitis is a globally prevalent chronic inflammatory disease triggered by dysregulation of oral biofilm and host immune responses, serving as the primary cause of adult tooth loss ( A multi-platform analysis of human gingival crevicular fluid reveals that ferroptosis is an associated regulated cell death mechanism during the clinical progression of periodontitis ( Porphyromonas gingivalis can actively induce ferroptosis through multiple pathways ( This review systematically summarizes the molecular mechanisms of ferroptosis in periodontitis, with a focus on how dysregulated iron metabolism, reprogrammed lipid metabolism, and suppressed antioxidant defenses in the periodontal microenvironment regulate ferroptosis

Lipid peroxidation damages sperm membranes, reducing fluidity and motility

Hemogram indices, including properties of platelets Rates across different cell types can provide valuable insights into inflammatory processes [5, 9, 29, 54]