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303 JAK-STAT signaling pathway During the aging process, sustained activation of the JAK-STAT signaling pathway induces the expression of the SASP, promoting cellular senescence and apoptosis, as well as impairing the function of T cells, B cells, and macrophages

The concentration of IFN and CCL5 in collected culture supernatants was measured using LEGEND MAX Mouse IFN- ELISA Kit (#439407, BioLegend) and Mouse RANTES ELISA Kit (#E-EL-M0009, Elabscience Biotechnology Co., Ltd) according to the manufacturer's instructions

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The unpaired genes within syntenic blocks between subgenomes possibly indicated the deletion of their homoeologs in the counterpart subgenome

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