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Peyron et al., 1994

Kao WK, Gagnon PM, Vogel JP, Chole RA

The involvement of mitochondria in ferroptosis as an important source of ROS is still the current mainstream view, since mitochondrial ROS (mitoROS) is mainly produced by oxidative phosphorylation (OXPHOS) complexes in mitochondria ( Although mitochondria are closely related to ROS production and iron metabolism, the causal relationship between morphological changes of mitochondria and ferroptosis remains unclear

You can even opt for supplements upon consultation with your doctor if you are vegan and lower the risks of deficiency-related complications

These enzymes tightly link to the pool of the redox buffers ascorbate, glutathione and pyridine nucleotides, which serve as reductants to recycle repeatedly glutathione and ascorbate via the so-called Foyer-Halliwell (or ascorbate-glutathione) cycle ( Figure 2 )