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Description
Am J Med Genet B, Neuropsychiatr Genet 2006

About 90% of patients experience a prodromal phase (63), that is characterized mainly by signs and symptoms of autonomic dysfunction such as pallor, sweating, lethargy, hot flashes and rarely temperature change and drooling (65)

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Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes

Research has examined whether carnitine supplementation can support mitochondrial function in aging models
