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This dose is typically given daily for the first week, followed by weekly injections for the first month, and then monthly maintenance doses

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PMID 31886171

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After oral treatment with betanin, they found that followed by a significant increase of glycolytic enzyme (glucokinase and pyruvate kinase), glucose6phosphate dehydrogenase, and decrease in the activity of gluconeogenic enzymes (glucose6phosphatase and fructose1,6bisphosphatase), the levels of plasma glucose, insulin, glycosylated hemoglobin (HbA1c), and hemoglobin (Hb) were restored in diabetic rat