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International Journal of Pharmaceutical Frontier Research

The trade-off is equally well-known

Another drug in this category is mazdutide (also known as IBI362 or LY3305677), which is potentially thought to offer superior therapeutic benefits compared to GLP-1R agonists alone

By preserving more NAD+ inside the cell, this dual approach may offer stronger, longer-lasting support for energy, mitochondrial function, inflammation regulation, and cellular repair
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